Ion-exchange PS-DVB Resin

Alkali-resistance Type

AstraChroma ion-exchange media base on PS-DVB microspheres. It has excellent mechanical property and can withstand pressures up to 10 MPA. 1000Å pore guarantee the free entry and exit of biomacromolecule. It is endowed with enough hydrophilicity by the unique coating technology of Biovanix, while the monodisperse particles effectively reduce column pressure and mass transfer barriers.
AstraChroma lEX media use “tentacle” surface derivation technology, Functional groups are covalently bonded on the substrate surface in the form of linear polymer chains. With a larger number of effective functional groups, its low steric hindrance enables macromolecules, antibodies, viruses, and plasmids to bind more effectively to the functional groups of the media, increasing the binding capacity significantly. “Tentacle” structure effectively reduces the non-specific interaction between biomolecules and media, thus improving the recovery of target molecules.

  • Rigid particles, low back-pressure, suitable for large-scale purification processes.
  • High flow rate, high loading capacity, high purification efficiency.
  • Not easy to decompose by microorganisms, reduce the risk of endotoxin contamination.
  • Excellent chemical stability, alkali cleaning conditions, long lifetime.
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Ion-exchange Resin Parameter

Product Poly15 SP Poly15 Q Poly30 SP Poly30 Q
Matrix Monodisperse PS-DVB
Particle Size 15um 30um
Function Group (-CH2)SO3- -CH2N+(CH3)3 (-CH2)SO3- -CH2N+(CH3)3
Ligand Density 0.22meq/mL 0.24meq/mL 0.15meq/mL 0.18meq/mL
Capacity 80mg Lys/mL 45mg BSA/mL 60mg Lys/mL 30mg BSA/mL
Flow Rate 150~800cm/h 250~1000cm/h
Max. Pressure 8.0MPa 5.0MPa
pH Stability 2-12
  Chemical Stability All commonly used buffers,1M acetic acid,1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea, and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50M
Matrix SP Q CM DEAE
Particle Size PS-DVB
Function Group 50um
Pore Size 100-150nm
Ligand Density 0.15meq/mL 0.16meq/mL 0.15me q/mL 0.16me q/mL
Capacity >80mgLys >100mg BSA >80mgLys >90mg BSA
Flow Rate 300~1200cm/h
Max Pressure 3.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50G
Matrix SP SP SP SP
Particle Size PS-DVB
Function Group 50um
Pore Size 150-300nm
Ligand Density 0.14me q/mL 0.14me q/mL 0.14me q/mL 0.14me q/mL
Capacity >70mg Lys >70mg Lys >70mg Lys >70mg Lys
Flow Rate 300~1200cm/h
Max Pressure 2.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50V
Matrix SP SP SP SP
Particle Size PS-DVB
Function Group 50um
Pore Size 300-400nm
Ligand Density 0.12me q/mL 0.12me q/mL 0.12me q/mL 0.12me q/mL
Capacity >70mg Lys >70mg Lys >70mg Lys >70mg Lys
Flow Rate 300~1200cm/h
Max Pressure 1.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol
Product Poly15 SP Poly15 Q Poly30 SP Poly30 Q
Matrix Monodisperse PS-DVB
Particle Size 15um 30um
Function Group (-CH2)SO3- -CH2N+(CH3)3 (-CH2)SO3- -CH2N+(CH3)3
Ligand Density 0.22meq/mL 0.24meq/mL 0.15meq/mL 0.18meq/mL
Capacity 80mg Lys/mL 45mg BSA/mL 60mg Lys/mL 30mg BSA/mL
Flow Rate 150~800cm/h 250~1000cm/h
Max. Pressure 8.0MPa 5.0MPa
pH Stability 2-12
  Chemical Stability All commonly used buffers,1M acetic acid,1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea, and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50M
Matrix SP Q CM DEAE
Particle Size PS-DVB
Function Group 50um
Pore Size 100-150nm
Ligand Density 0.15meq/mL 0.16meq/mL 0.15me q/mL 0.16me q/mL
Capacity >80mgLys >100mg BSA >80mgLys >90mg BSA
Flow Rate 300~1200cm/h
Max Pressure 3.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50G
Matrix SP SP SP SP
Particle Size PS-DVB
Function Group 50um
Pore Size 150-300nm
Ligand Density 0.14me q/mL 0.14me q/mL 0.14me q/mL 0.14me q/mL
Capacity >70mg Lys >70mg Lys >70mg Lys >70mg Lys
Flow Rate 300~1200cm/h
Max Pressure 2.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

 

Product Poly 50V
Matrix SP SP SP SP
Particle Size PS-DVB
Function Group 50um
Pore Size 300-400nm
Ligand Density 0.12me q/mL 0.12me q/mL 0.12me q/mL 0.12me q/mL
Capacity >70mg Lys >70mg Lys >70mg Lys >70mg Lys
Flow Rate 300~1200cm/h
Max Pressure 1.0MPa
pH Stability 1-12
Chemical Stability All commonly used buffers, 1M acetic acid, 1M sodium oxychloride, 1M hydrochloric acid, 70% ethanol 30% isopropyl alcohol, 30% acetonitrile, 1%SDS, 6M guanidine hydrochloride, 8M urea and other commonly used organic solvents; Avoid exposure to strong oxidants.
Usage Temperature 4~30°C
Storage 2~30°C, 20% ethanol

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